Linearity and Instrumentation

www.cap.org

Calibration Verification/Linearity and Instrumentation Analytes/procedures in bold type are regulated for proficiency testing by the Centers for Medicare & Medicaid Services (CMS).

Your Total Calibration Verification/Linearity (CVL) Solution Calibration Verification/Linearity Survey Corresponding Survey Survey Validated Material LN1-Chemistry CVL C1, C3, CZ LN2ERVM LN1ER-Chemistry Extended Range CVL C1, C3, CZ LN2ERVM LN2-Chemistry/Lipid/Enzyme CVL C1, C3, CZ LN2ERVM LN2ER-Chemistry/Lipid/Enzyme/Extended Range CVL C1, C3, CZ LN2ERVM LN3-TDM CVL CZ, Z CZVM LN5-Ligand Assay CVL K, KK, KN LLM LN6-Urine Chemistry CVL U LUM LN7-Immunology CVL IG LN8-Reproductive Endocrinology CVL Y, YY LN9-Hematology CVL FH Series, HE Series LN9ER-Hematology Extended Range CVL FH Series, HE Series LN11-Serum Ethanol CVL AL2 LN11ER-Serum Ethanol Extended Range CVL AL2 LN12-C-Reactive Protein CVL CRP LN13, LN13C-Blood Gas/Critical Care CVL AQ, AQ2 LN14-Whole Blood Ethanol CVL AL1 LN15-Glycohemoglobin CVL GH2 LN16-Homocysteine CVL HMS LN17-Whole Blood Glucose CVL WBG, WB2 LN18-Reticuloctye CVL RT, RT2, RT3, RT4 LN19-Reticulocyte CVL RT3 (Coulter GenS and LH700 series only) LN20-Microalbumin CVL U (Microalbumin and Creatinine) LN21-High-Sensitivity C-reactive Protein CVL hsCRP LN22-Flow Cytometry CVL FL LN23-Prostate-Specific Antigen CVL K (PSA) LN24-Creatinine Accuracy CVL C1, C3, CZ LN25-Troponin I CVL TRP, CRT LN26-Troponin I CVL TRP (Abbott AxSYM only) LN27-Troponin T CVL TRP, CRT (Troponin T) LN28-Adjustable Micropipette CVL LN30-B-type Natriuretic Peptides CVL BNP LN31-Immunosuppressive Drugs CVL CS LN32-Ammonia CVL NEW LN33-Serum Myoglobin CVL NEW CARM, CRT, CARMI, CRTI LN34-CA-125 CVL NEW TM Provides individual evaluation reports by analyte, executive summary report, and graphical plots for linearity and calibration verification.

2007 Surveys & Anatomic Pathology Education Programs Calibration Verification/Linearity and Instrumentation

77

800-323-4040 Option 1 # for Customer Contact Center

Calibration Verification/Linearity Surveys advantages: ❚

Receive liquid specimens that cover broad analyte ranges to challenge assays from near zero to the top of the analytical measurement range for most analytes and methods

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Access a comprehensive selection of analytes and programs to encompass a broad testing menu

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Satisfy the requirements for scheduled verification of the analytical measurement range of the CAP Laboratory Accreditation Program and the CLIA calibration verification under 42 CFR493.1255(b)(3) for most analytes

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Use a consistent analytical approach for the assessment of the method linearity and calibration agreement with your peer group

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Get custom reports with an Executive Summary for a quick overview of the performance, a Comprehensive Evaluation Report with specific analyte information, and Linearity & Calibration/Verification graphs

Note: The College of American Pathologists Laboratory Accreditation Program requires an additional calibration verification process for methods calibrated less frequently than once every six months. Please review the inspection checklist for information about suitable verification material for any method that is calibrated less often than at six-month intervals. The Calibration Verification/Linearity Surveys are designed to assess agreement of a laboratory with the method manufacturer’s calibration settings, but do not validate accuracy traceable to reference methods. Please see the CAP Standards and Instrumentation Resource Committee Web site at www.cap.org or contact a CAP Customer Contact Center Representative at 800-323-4040 option 1 # for additional information and a listing of the specific analyte ranges targeted in these Surveys.

Improve the reliability of your patient results with CAP Survey Validated Materials Use the same material that is sent in the Surveys Program to: ❚

Identify and troubleshoot instrument/method problems

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Correlate results with other laboratories or instruments

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Document correction of problems identified in Surveys

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Utilize as an alternative external quality control material with confirmed results

Results are readily available in the Survey Participant Summary that is included with each Survey Evaluation Report.

College of American Pathologists 78

Calibration Verification/Linearity and Instrumentation

www.cap.org

Chemistry/Lipid/Enzyme Calibration Verification/Linearity LN1, LN1ER, LN2, LN2ER Analyte Albumin Bilirubin, direct Bilirubin, total* Calcium* Chloride CO2* Creatinine Glucose Iron Magnesium Osmolality* Phosphorus Potassium Protein, total Sodium Urea Uric Acid Alanine aminotransferase (ALT/SGPT) Alkaline phosphatase (ALP) Amylase Aspartate aminotransferase (AST/SGOT) Cholesterol* CK2 (MB) Creatine kinase (CK) Gamma glutamyl transferase (GGT) HDL cholesterol* Lactate dehydrogenase (LD) Lipase Triglycerides* Auto dilutor validation report NEW

LN1

LN1ER

LN2

LN2ER

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❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚

CVL CHEMISTRY/LIPID/ENZYME VALIDATED MATERIAL (LN2ERVM)

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$594

Product Information New for 2007: LN1 and LN2 participants will be allowed to report auto diluted specimen results. A report will be provided that may be used to verify that the auto dilutor is working appropriately. Surveys LN1 and LN2 correspond to CAP Chemistry Surveys C1, C3, and CZ. Each shipment of Surveys LN1 and LN2 will contain six 10.0-mL liquid serum specimens and six 3.0-mL liquid serum specimens for evaluation of direct and total bilirubin. Each shipment of Survey LN2 will also contain one 20.0-mL and two 10.0-mL liquid lipid serum specimens from which additional admixtures will be prepared. Survey LN1ER will include all specimens in LN1 and an additional high vial for participants that need higher analyte ranges than currently available in Survey LN1. Survey LN2ER will include all specimens in LN2 and an additional high vial for participants that need higher analyte ranges than currently available in Survey LN2. Note: The extended range vial (LN1ER and LN2ER) will be evaluated for calibration verification only. Each set of LN2ERVM ordered will contain all the specimens included in LN2ER. Ship Dates Shipment A June 18 Shipment B December 10

*These analytes are not available for extended range reporting.


79


Product Information Survey LN3 corresponds to CAP General Chemistry and Therapeutic Drug Monitoring Surveys CZ and Z. Each shipment of Survey LN3 will include six 4.0-mL liquid serum specimens. Each set of LDM ordered will consist of six 4.0-mL liquid serum specimens. Ship Dates Shipment A May 7 Shipment B November 5

TDM Calibration Verification/Linearity Analyte Acetaminophen Amikacin Carbamazepine Digoxin Gentamicin Lidocaine Lithium N-acetylprocainamide (NAPA) Phenobarbital Phenytoin Primidone Procainamide Quinidine Salicylate Theophylline Tobramycin Valproic acid Vancomycin

LN3 ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚

CVL TDM VALIDATED MATERIAL (LDM)

Product Information Survey LN5 corresponds to CAP Ligand Assay (General) Surveys K, KK, and KN. Each shipment of Survey LN5 will include five 4.0-mL liquid serum specimens. Each set of LLM ordered will consist of five 4.0-mL liquid serum specimens. Ship Dates Shipment A June 4 Shipment B November 26

LN3

$202

Ligand Assay Calibration Verification/Linearity LN5 Analyte CEA Cortisol Ferritin Folate Human chorionic gonadotropin (hCG) T3, total (Triiodothyronine) T4, total (Thyroxine) Thyroid-stimulating hormone (TSH) Vitamin B12

LN5

CVL LIGAND ASSAY VALIDATED MATERIAL (LLM)

$204

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www.cap.org

Urine Chemistry Calibration Verification/Linearity LN6

Product Information New for 2007: LN6 participants will be allowed to report auto diluted specimen results. A report will be provided that may be used to verify that the auto dilutor is working appropriately. Survey LN6 corresponds to CAP Urine Chemistry (General) Survey U. Each shipment of Survey LN6 will include ten 4.0-mL liquid urine specimens.

Analyte Amylase Calcium Chloride Creatinine Glucose Osmolality Phosphorus Potassium Protein, total Sodium Urea Uric acid Auto dilutor validation report NEW

LN6

CVL URINE CHEMISTRY VALIDATED MATERIAL (LUM)

$230

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Each set of LUM ordered will consist of ten 4.0-mL liquid urine specimens. Ship Dates Shipment A May 7 Shipment B November 5

Immunology Calibration Verification/Linearity LN7 Analyte Alpha-1-antitrypsin Complement C3 Complement C4 IgA IgG IgM Transferrin

LN7

PRICE

$376

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Product Information Survey LN7 corresponds to CAP Immunology (General) Survey IG. Each shipment of Survey LN7 will include five 2.0-mL liquid serum specimens. Ship Dates Shipment A April 9 Shipment B October 1


81


Reproductive Endocrinology Calibration Verification/Linearity LN8 Analyte Estradiol Follicle-stimulating hormone (FSH) Human chorionic gonadotropin (hCG) Luteinizing hormone (LH) Progesterone Prolactin Testosterone

LN8

PRICE

$376

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Product Information Survey LN8 corresponds to CAP Ligand Assay (Special) Surveys Y and YY. Each shipment of Survey LN8 will include five 4.0-mL liquid serum specimens. Ship Dates Shipment A April 10

Shipment B October 1

Hematology Calibration Verification/Linearity Analyte Hemoglobin Platelet count RBC count WBC count PRICE

LN9 ❚ ❚ ❚ ❚

$596

LN9, LN9ER LN9ER ❚ ❚

$624

Product Information Surveys LN9 and LN9ER correspond to the CAP Basic Hematology and Hematology Automated Differentials Surveys HE and FH series. Surveys LN9 and LN9ER are compatible with all instruments. The Surveys provide an indicator of platelet accuracy at clinical decision levels. The specimens are designed to span the linear range of most automated hematology instruments. Each shipment of LN9 will include 18 3.0-mL specimens. Survey LN9ER will include all specimens in LN9 and four additional high vials for participants that need higher platelet and WBC ranges than currently available in Survey LN9. Note: The extended range vial will be evaluated for calibration verification only. All vials have pierceable caps. Ship Dates Shipment A April 10




www.cap.org

Serum Ethanol Calibration Verification/Linearity

LN11, LN11ER

Analyte Serum Ethanol

LN11

LN11ER

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PRICE

$338

$350

Product Information Surveys LN11 and LN11ER correspond to the AACC/CAP Serum Alcohol/Volatiles Survey (AL2). Each shipment will contain six 3.0-mL liquid serum specimens. Survey LN11ER will include all specimens in LN11 and one additional high vial for participants that need higher analyte ranges than currently available in Survey LN11. Note: The extended range vial will be evaluated for calibration verification only. Ship Dates Shipment A January 29

Shipment B August 6

C-reactive Protein Calibration Verification/Linearity

LN12

Analyte C-reactive protein

LN12

PRICE

$318

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Product Information Each shipment of Survey LN12 will include six 1.0-mL liquid serum specimens. Note: This Survey is not designed for reporting high-sensitivity C-reactive protein. Ship Dates Shipment A January 29

Shipment B August 6


83


Blood Gas/Critical Care Calibration Verification/Linearity LN13, LN13C Analyte PCO2 pH PO2 Calcium, ionized Chloride Glucose Lactate Magnesium, ionized Potassium Sodium

LN13

LN13C

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PRICE

$404

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$486

Product Information Survey LN13 corresponds to the blood gas component of the CAP Critical Care Aqueous Blood Gas AQ/AQ2 Surveys. Survey LN13C corresponds to the electrolyte and blood gas components of the AQ/AQ2 Surveys. Each shipment of Survey LN13 and LN13C will include ten 2.5-mL ampules of aqueous specimens (five in duplicate) for single instrument reporting. Ship Dates Shipment A January 29

Shipment B August 6

Whole Blood Ethanol Calibration Verification/Linearity Analyte Ethanol

LN14

PRICE

$392

LN14

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Product Information Survey LN14 corresponds to the AACC/CAP Alcohol/Volatiles Survey (AL1) for whole blood analysis of ethanol. Each shipment of Survey LN14 will include six 3.0-mL liquid whole blood specimens. Ship Dates Shipment A January 29

Shipment B August 6



www.cap.org

Glycohemoglobin Calibration Verification/Linearity

LN15

Analyte Glycohemoglobin (HbA1c)

LN15

PRICE

$414

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Product Information Survey LN15 corresponds to the CAP GH2 Survey for glycohemoglobin. Each shipment of Survey LN15 will include six 0.7-mL liquid human whole blood specimens. Note: These specimens must be processed as patient specimens, and tested as soon as possible after they are received. Ship Dates Shipment A March 6


Homocysteine Calibration Verification/Linearity

LN16

Analyte Homocysteine

LN16

PRICE

$542

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Product Information Survey LN16 corresponds to the CAP HMS Survey for homocysteine. Each shipment of Survey LN16 will include six 1.0-mL liquid serum specimens. Ship Dates Shipment A March 12

Shipment B September 17

Whole Blood Glucose Calibration/Verification Linearity

LN17

Analyte Whole blood glucose

LN17

PRICE

$262

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Product Information Survey LN17 corresponds to the CAP WBG/WB2 Surveys for whole blood glucose. With each kit, you may report from ten different ancillary testing sites or instruments. Each shipment of Survey LN17 will include five 2.0-mL liquid whole blood specimens. Ship Dates Shipment A March 12



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Reticulocyte Calibration Verification/Linearity Instrument All instruments except Coulter GenS and LH700 series Coulter GenS and LH700 series Pierceable caps

LN18

PRICE

$416

LN18, LN19 LN19

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$416

Product Information Survey LN18 corresponds to the CAP RT, RT2, RT3, and RT4 Surveys for all instruments except the Coulter GenS and LH700 series. Survey LN19 corresponds to the RT3 Survey for Coulter GenS and LH700 series users only. Each shipment of Surveys LN18 and LN19 will include five 1.0-mL red blood cell specimens. Ship Dates Shipment A March 26


Microalbumin Calibration Verification/Linearity

LN20

Analyte Microalbumin Creatinine

LN20

PRICE

$312

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Product Information Survey LN20 corresponds to CAP Urine Chemistry Survey U. Each shipment of Survey LN20 will include five 5.0-mL liquid urine specimens. Ship Dates Shipment A April 10


High-Sensitivity C-reactive Protein Calibration Verification/Linearity LN21 Analyte High-sensitivity C-reactive protein

LN21

PRICE

$338

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Product Information Survey LN21 corresponds to the CAP High-Sensitivity C-reactive Protein Survey hsCRP. Each shipment of Survey LN21 will include six liquid serum specimens. Survey LN21 is for high sensitivity methods only. Ship Dates Shipment A April 10




www.cap.org

Flow Cytometry Calibration Verification/Linearity

LN22

Analyte CD3+ CD3+/CD4+ CD3+/CD8+

LN22

PRICE

$636

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Product Information Survey LN22 corresponds to the CAP Flow Cytometry Survey FL. Each shipment of LN22 will include seven 1.0-mL liquid whole blood specimens. Ship Dates Shipment A April 2


Prostate-Specific Antigen Calibration Verification/Linearity Analyte Prostate-Specific Antigen

LN23

PRICE

$812

LN23

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Product Information Survey LN23 corresponds to the CAP Ligand Assay Survey K. Each shipment of LN23 will include twelve 1.0-mL liquid serum specimens. The first seven vials will consist of values specified at a range from 0.1-4.0 ng/mL. Vials eight through twelve will consist of values specified at a range from 8.0-90.0 ng/mL. Ship Dates Shipment A May 21

Shipment B November 26

Creatinine Accuracy Calibration Verification/Linearity

LN24

Analyte Creatinine

LN24

PRICE

$382

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Product Information The LN24 Survey focuses on values for creatinine at the range from 0.5-4.0 mg/dL. Each shipment of LN24 will consist of seven 1.0-mL liquid fresh frozen serum specimens. Ship Dates Shipment A May 21



87


Troponin I Calibration Verification/Linearity Instrument All instruments except Abbott AxSYM Abbott AxSYM

LN25

PRICE

$652

LN25, LN26 LN26

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$652

Product Information Surveys LN25 and LN26 correspond to the CAP Troponins I and T Survey TRP. Each shipment of LN25 will consist of seven 2.0-mL liquid serum specimens. Each shipment of LN26 will consist of five 2.0-mL liquid serum specimens. Note: The specimens must be processed and tested as soon as possible after they are received. Ship Dates Shipment A March 26


Troponin T Calibration Verification/Linearity

LN27

Analyte Troponin T

LN27

PRICE

$652

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Product Information Survey LN27 corresponds to the CAP Troponins I and T Survey TRP. Each shipment of LN27 will consist of six 2.0-mL liquid serum specimens. Note: The specimens must be processed and tested as soon as possible after they are received. Ship Dates Shipment A March 26


Adjustable Micropipette Calibration Verification/Linearity Challenge Adjustable Micropipette

LN28

PRICE

$250

LN28

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Product Information Survey LN28 is designed to calibrate up to five adjustable micropipettes using a spectrophotometer or microtiter plate reader. Survey LN28 will consist of a 20.0-mL chromophore vial. Ship Dates Shipment A April 2

Shipment B December 3



www.cap.org

B-type Natriuretic Peptides Calibration Verification/Linearity LN30 Analyte BNP NT-pro BNP

LN30

PRICE

$422

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Product Information Survey LN30 corresponds to the CAP B-type Natriuretic Peptides Survey BNP. Each shipment of LN30 will include six 1.0-mL liquid plasma specimens for BNP and NT-pro BNP. A seventh 1.0-mL liquid plasma specimen will be included to test only for NT-pro BNP. Note: Linearity Surveys have linearity targets based on clinical relevance and general characteristics of currently available methods. These criteria may not be reflective of the specific characteristics of the currently available single dose unit technology methods. For customers using single dose unit technology, it is the laboratory's discretion to assess the appropriateness of the linearity targets when applied to this technology and to the clinical needs of their patients Ship Dates Shipment A June 11

Shipment B December 10

Immunosuppressive Drugs Calibration Verification/Linearity LN31 Analyte Cyclosporine Tacrolimus

LN31

PRICE

$852

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Product Information Survey LN31 corresponds to the CAP Immunosuppressive Drugs CS Survey. Each shipment of LN31 will include seven 2.0-mL liquid EDTA plasma specimens. Ship Dates Shipment A February 26

Shipment B August 27


89

800-323-4040 Option 1 # for Customer Contact Center New

Ammonia Calibration Verification/Linearity

LN32

Analyte Ammonia

LN32

PRICE

$422

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Product Information Each shipment of LN32 will include seven 2.0-mL liquid specimens. Ship Dates Shipment A May 21

New


Serum Myoglobin Calibration Verification/Linearity

LN33

Analyte Myoglobin

LN33

PRICE

$422

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Product Information Survey LN33 corresponds to the CAP Cardiac Markers CARM, CRT, CARMI, and CRTI Surveys for quantitative myoglobin. Each shipment of LN33 will include seven 1.0-mL liquid specimens. Ship Dates Shipment A May 21

New


CA-125 Calibration Verification/Linearity

LN34

Analyte CA-125

LN34

PRICE

$422

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Product Information Each shipment of LN34 will include seven 3.0-mL liquid specimens. Ship Dates Shipment A April 23




www.cap.org

Reference Range Service RRS Analyte Alanine aminotransferase Albumin Amylase Aspartate aminotransferase Bilirubin, total Calcium CK-MB Creatinine Ferritin T4, free (thyroxine, free) Iron Lactate dehydrogenase Magnesium Protein, total T4 (thyroxine) Total iron binding capacity Thyroid stimulating hormone (TSH) PRICE

New

RRS, RRS2 RRS2

RRS ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚ ❚

Analyte RRS2 B-type Natriuretic Peptides (BNP) ❚ Pro B-type Natriuretic Peptides (NT-pro BNP) ❚ Chloride ❚ CO2 ❚ C-reactive Protein (CRP) ❚ Folate ❚ Gamma Glutamyl Transferase (GGT) ❚ Glucose ❚ Potassium ❚ Sodium ❚ Testosterone ❚ Thrombin Time (TT) ❚ Uric Acid ❚ Urea ❚ Vitamin B-12 ❚

$243

Product Information The Reference Range Service (RRS and RRS2) is designed for laboratories/laboratory networks to provide a method to establish and/or verify the validation of reference intervals based on the NCCLS Reference Range Protocol C28-A2, Vol. 15, No. 4 entitled, “How to Define and Determine Reference Intervals in the Clinical Laboratory; Approved Guideline – Second Edition,” non parametric approach. Laboratories will be required to submit 20 results for each analyte, validated from “normal/healthy” individuals. Exclusionary criteria will be provided to facilitate identification of appropriate donors. In addition, the participating laboratory will submit testing methods and instruments as well as gender, age, and race of each donor, using classifications from the United States Office of Management and Budget, Revisions to the Standards for the Classification of Federal Data on Race and Ethnicity (Federal Register Notice, October 30, 1997). Laboratories participating in the RRS and RRS2 will receive a summary report including the reference interval for each analyte for which data is submitted. The reference intervals will be provided by platform. In February 2007 participants will be requested to provide their instruments/reagents/methods to ensure that the minimum number of data sets are available per platform for analysis. In addition, laboratories will be provided with exclusionary criteria for potential donors. All donor results should be returned to the CAP for analysis, including those that may be outside of your laboratory’s established reference interval. Note: The College had determined that Institutional Review Board (IRB) review is not routinely required to participate in this reference interval service. However, if the laboratory is in an instituion that requires IRB review to conduct reference interval studies, be advised that the deadline to return donor results to the CAP will be May. Ship Dates

Shipment A May 14


91


Instrumentation

I

Instrument Spectrophotometer Linearity pH Meters: Buffers for pH measurements Wavelength and Photometric Calibration: Acid potassium dichromate solutions—absorbance check, autodilutor check Holmium oxide—peak absorbance Thomson’s solutions—wavelength and photometric calibration Analytical balance Fluorescent microscopes Microtiter plate reader linearity Ocular micrometer Osmometer Pipette calibration, gravimetric Adjustable micropipette calibration verification/linearity Refractometer

A

Survey Shipment B

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PRICE $462 Product Information Survey I is designed as an assessment tool for instruments not routinely challenged during the proficiency testing process. Linearity results (forward and reverse) for the spectrophotometer and microtiter plate reader are evaluated by linear regression methods. Appropriate material will be provided to assess important functional parameters, including accuracy and linearity. Please note that some challenges in the I Survey, B shipment, may contain chemically hazardous material and will require special handling. The kit instructions and the specimen vials will identify if any chemically hazardous material is present. Ship Dates Shipment A April 2

Shipment B July 30

Shipment C December 3



www.cap.org

Serum Carry Over Survey

SCO

Analyte Creatinine hCG Lactate dehydrogenase (LD) Phenytoin

SCO

PRICE

$346

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Product Information The Survey SCO is designed to help participants prove or disprove instrument sample probe carry over. Multiple kits may be purchased. Each shipment of SCO will consist of a 10.0-mL liquid serum specimen low vial and a 5.0-mL liquid serum high vial. The expiration date of this material is May 31, 2008. A calculation is provided in the kit instructions to assist the participants in determining their instrument sample probe carry over; therefore, data need not be returned to the CAP. Ship Date Shipment A May 14

Urine Toxicology Carry Over Survey

UTCO

Analyte Benzoylecgonine Delta-9-THC-COOH Opiates Propoxyphene

UTCO

PRICE

$296

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Product Information The Survey UTCO is designed to help participants evaluate instrument sample probe carry over. Multiple kits may be purchased. Each shipment of UTCO will consist of a 40.0-mL liquid urine specimen low vial and a 40.0-mL liquid urine high vial. The expiration date of this material is May 31, 2008. A calculation is provided in the kit instructions to assist the participants in determining their instrument sample probe carry over; therefore, data need not be returned to the CAP. Ship Date Shipment A May 14


93


Product Information Survey IFS is designed to assist participants in verifying manufacturing interference specifications and to investigate discrepant results caused by interfering substances such as bilirubin and hemoglobin. Multiple kits may be purchased. Each shipment of IFS will consist of twelve 10.0-mL liquid serum specimens. The expiration date of this material is June 30, 2008. Laboratories may send their results to the CAP for evaluation through the expiration date of the material. Participants will receive their evaluations one week after the results have been received by the CAP. Ship Date Shipment A June 11

Interfering Substance Survey Analyte Alanine aminotransferase (ALT/SGPT) Albumin Alkaline phosphatase (ALP) Amylase Aspartate aminotransferase (AST/SGOT) Bilirubin, total Calcium Chloride CK2 (MB) CO2 Creatine Kinase (CK) Creatinine Gamma glutamyl transferase (GGT) Glucose Iron Lactate dehydrogenase (LD) Lipase Magnesium Osmolality Phosphorus Potassium Protein, total Sodium Urea Uric Acid PRICE

IFS

Bilirubin Interferent

Hemoglobin Interferent

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$368



Linearity and Instrumentation

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