The Patient Health Questionnaire-2 (PHQ-2) - Overview The PHQ-2 inquires about the frequency of depressed mood and anhedonia over the past two weeks...
The Patient Health Questionnaire (PHQ-9) - Overview The PHQ-9 is a multipurpose instrument for screening, diagnosing, monitoring and measuring the severity of depression:
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The Patient Health Questionnaire-2 (PHQ-2) - Overview The PHQ-2 inquires about the frequency of depressed mood and anhedonia over the past two weeks. The PHQ-2 includes the first two items of the PHQ-9. n The purpose of the PHQ-2 is not to establish final a diagnosis or to monitor depression severity, but rather to screen for depression in a “first step” approach. n Patients who screen positive should be further evaluated with the PHQ-9 to determine whether they meet criteria for a depressive disorder. Clinical Utility Reducing depression evaluation to two screening questions enhances routine inquiry about the most prevalent and treatable mental disorder in primary care. Scoring A PHQ-2 score ranges from 0-6. The authors1 identified a PHQ-2 cutoff score of 3 as the optimal cut point for screening purposes and stated that a cut point of 2 would enhance sensitivity, whereas a cut point of 4 would improve specificity. Psychometric Properties1 Major Depressive Disorder (7% prevalence) Any Depressive Disorder (18% prevalence) PHQ-2 Sensitivity Specificity Score
Positive PHQ-2 Sensitivity Specificity Predictive Score Value (PPV*)
Positive Predictive Value (PPV*)
1
97.6
59.2
15.4
1
90.6
65.4
36.9
2
92.7
73.7
21.1
2
82.1
80.4
48.3
3
82.9
90.0
38.4
3
62.3
95.4
75.0
4
73.2
93.3
45.5
4
50.9
97.9
81.2
5
53.7
96.8
56.4
5
31.1
98.7
84.6
6
26.8
99.4
78.6
6
12.3
99.8
92.9
* Because the PPV varies with the prevalence of depression, the PPV will be higher in settings with a higher prevalence of depression and lower in settings with a lower prevalence.
1. Kroenke K, Spitzer RL, Williams JB. The Patient Health Questionnaire-2: Validity of a Two-Item Depression Screener. Medical Care 2003, (41) 1284-1294.
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The Patient Health Questionnaire-2 (PHQ-2) Patient Name ______________________________________ Date of Visit ________________ Over the past 2 weeks, how often have Not Several More Nearly you been bothered by any of the At all Days Than Half Every following problems? the Days Day