WHO STAGING SYSTEM FOR HIV INFECTION AND DISEASE

Download WHO staging system for HIV infection and disease: a clinical / laboratory classification. Laboratory Group. Clinical group. Lymphocyte coun...

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WHO staging system for HIV infection and disease: a clinical / laboratory classification

Laboratory Group

Clinical group

Lymphocyte count CD4 count (x 106/litre) (x 106/1)

1 2 Asymptomatic Early

3 4 Intermediate Late

A >2000

>500

1A

2A

3A

4A

B 1000 - 2000

200 - 500

1B

2B

3B

4B

C <1000

<200

1C

2C

3C

4C

Group 1: asymptomatic or persistent generalized lymphadenopathy – normal activity Group 2: early-stage disease – weight loss <10 per cent of body weight, minor mucocutaneous manifestations, herpes zoster within 5 years, recure upper respiratory tract infections, symptomatic but normal activity. Group 3: intermediate stage disease – weight loss >10 per cent of body weight, unexplained chronic diarrhoea for more than1 month, infected prolonged fever for more than 1 month, oral candidiasis, oral hairy leucoplakia, pulmonary tuberculosis within 1 year, severe bacterial infection and/or bedridden less than 50 per cent of the day during the previous month. Group 4: late-stage disease – definite or presumptive diagnosis of any AIDS defining illness, according to the Centers for Disease Control the surveillance definition and/or bedridden for more than 50 per cent of the day during the previous month.