Additional file 2: Figure S2 - Springer

Additional file 2: Figure S2  

TMD  I    

Mmer Smod Tmur Bnec Pjap Ckis Vgar Llot Mpou Pvir Ppol Mmea Maeg Tfin Tcha Goga Gmor Gmac Mpro Bsai Agla Ulom Hsap

                         TMD  IV     Mmer Smod Tmur Bnec Pjap Ckis Vgar Llot Mpou Pvir Ppol Mmea Maeg Tfin Tcha Goga Gmor Gmac Mpro Bsai Agla Ulom Hsap

 

               TMD  III  

             Insert    

 

 

 

 TMD  V  

_______________________ _____________________ AAALFYFLLVFGGAFWFFGGGYGAGWASVEEVVAFPAIFGDPFDEVINFSVISGDAAGVGMLYSLGGGLLVLSAWVLLLTLFVVLEVT GSVLGYFSLVLGALFWFVGGWHEGAWV--------------PADELIEFSVVSGDSAGVAMMYSLGGGMLIIGAWVLLLALFVVLELA GYALGYLLSVLGALSWFWGGWYEGGWV--------------PVNELVEFSVVPGDSGGVALMYSSGGGFLVVGAWVLLLALFVVLELA GAVGGYLVVIMGAVIWFYNSLSEGEWL--------------TSEDTDGKGVFGLDSEGVALMYSSGGGLLILSAWVLLLTLFVVLSVT SVIAGYVALLAGGTVFFMEEWYQYIWV--------------PESKSSDYGLIIPDVGGAGVMYHQGAGMLLIGAFVLLLTLFVVLEIC GALVGVVVGYSVAVIVGWVNWFGVGSE--------------SGYDFDDYSFICPEGEGLGLLYDKGGWLLLFCVIILLVVLVVVLELT MVLVGITVSWTAAAVFNWLDWSSLALL--------------NTYDYGDFTLLYPEGEGLSLMYDDGGWFLFFCVYVLLVVLALVLEVT GSVLGYLLLVFGGVSWFWGGWYEGAWV--------------PVDELIEFSVVAADSGGVALMYSLGGGLLVVSAWVLLLTLLVVLELT GSVLGYLLLVVGAGSWFWEGWYEAMWV--------------PVDELIEFSVVAADSGGVALMYSLGGGLLVASAWVLLLTLLVVLELT GSVLGYLLLVLGAGSWFWGGWYEGMWV--------------PVDELIEFSVVAADSGGVALMYSLGGGLLVVSAWVLLLTLLVVLELT GSVLGYLLLVLGAGSWFWGGWYEGMWV--------------PVDELIEFSVVAADSGGVALMYSLGGGLLVVSAWVLLLTLLVVLELT GAVLGYLLLVVGAGSWFWGGWYEGMWV--------------PVDELIEFSVVEADSGGVALMYSLGGGLLVVSAWVLLLTLLVVLELT GSAMGYLLLVVGAGSWFWGGWYEGMWV--------------PVDELIEFSVVAADLGGVALMYSLGGGLLVVSAWVLLLTLLVVLELT GSVLGYLLLVVGAGSWFWGGWYEGMWV--------------PVDELIEFSVVAADSGGVALMYSLGGGLLVVSAWVLLLTLLVVLELT GSVLGYLLLVVGAGSWFWGGWYEGMWV--------------PVDELIEFSVVAADSGGVALMYSLGGGLLVVSAWVLLLTLLVVLELT GSVLGYLLLVVGAGSWFWGGWYEGMWV--------------PVDELIEFSVVAADSGGVALMYSLGGGLLVVSAWVLLLTLLVVLELT GSVLGYLLLVVGAGSWFWGGWYEGMWV--------------PVDELIEFSVVAADSGGVALMYSLGGGLLVVSAWVLLLTLLVVLELT GSVLGYLLLVVGAGSWFWGGWYEGMWV--------------PVDELIEFSVVAADSGGVALMYSLGGGLLVVSAWVLLLTLLVVLELT GSVLGYLLLVLGAGSWFWGGWYEGMWV--------------PVDELIEFSVTAADSGGVALMYSLGGGLLVVSAWVLLLTLLVVLELT GSVLGYLLLVLGAGSWFWGGWYEGMWV--------------PVDELIEFSVVAADSGGVALMYSLGGGLLVVSAWVLLLTLLVVLELT GSVLGYLLLVVGAGSWFWGGWYEGMWV--------------PVDELIEFSVVAADSGGVALMYSLGGGLLVASAWVLLLTLLVVLELT GYGMGFVAVLVMGMVVGGFECWDLGVV--------------TVDSVGMFSV-RLDFGGVAMFYSCGVGMFLVAGWGLLLTLFVVLELV LVSVLVGLAMEVGLVLWVKEYDGVVVV-----VNFNSVGSWMIYEGEGSGLIREDPIGAGALYDYGRWLVVVTGWTLFVGVYIVIEIA

  Mmer Smod Tmur Bnec Pjap Ckis Vgar Llot Mpou Pvir Ppol Mmea Maeg Tfin Tcha Goga Gmor Gmac Mpro Bsai Agla Ulom Hsap

                 TMD  II  

___________________ ___________________ ________________________ MAYLMLSFLVGMIVGVISVASNPSPYFGALGLVLMAGAGCGCLIGHGGAFLAVVLFLIYLGGMLVVFAYCAALAAEPYPEAWGDVEVF MTYVMLTLLIGVIFGVISVASNPSPYFAALGLVLLAGVGCGILIGHGGSFLSLVLFLIYLGGMLVVFAYCAALAAEPYPEAWGEWSIL MAYMMLILLVGVIFGVISVASNPSPYFAALGLVLLAGVGCGILMGHGGSFLSLVLFLIYLGGMLVVFAYCAALAAEPYPEAWGEWAIM MSYVLILILIGMILGVVSVVSSPSPYFAALGLVVMAAAGCSVLVVSGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPEAWGEWSVL MMYL-LVVLAVMNLGVIFVASNPTPNFASLGLVFAAGLGCVVVLGSGGSFLALVLFLIYLGGMLVVFAYCVALAAEEYPEGLGAWSVS MFYMMMMMMVGFVLGAAALASNPSPVYAVLGLVLMAGMACMILINSGGPFLSLLFFLVYLGGMLVVFAHCVALAAERYPKAWGDVIFL MSYSMMMLSGVFILGAVALASSPSPVYAALGLVLMAGGASMLLIDSGGPFLSLLFYLVYLGGVLVVFAHCVALAADNYPKAWGDVILL MAYIMLTLLIGMVLGVISVASNPSPYFAALGLVLVAGVGCGVLMGHGGSFLSLVLFLIYLGGMLVVFAYCAALAAEPYPEAWGEWSVL MAYIMLTLLVGMVLGVISVASNPSPYFAALGLVLVAGVGCVILMGHGGSFLSLVLFLIYLGGMLVVFAYCAALAAEPYPEAWGEWSVL MAYIMLTLLIGMVLGVISVASNPSPYFAALGLVLVAGVGCVVLMGHGGSFLSLVLFLIYLGGMLVVFAYCAALAAEPYPEAWGEWSVL MAYIMLTLLVGMVLGVISVASNPSPYFAALGLVLVAGVGCVVLMGHGGSFLSLVLFLIYLGGMLVVFAYCAALAAEPYPEAWGEWSVL MAYIMLTLLVGMVLGVISVASNPSPYFAALGLVLVAGVGCVVLMGHGGSFLSLVLFLIYLGGMLVVFAYCAALAAEPYPEAWGEWSVL MAYIMLTLLIGMVLGVISVASNPSPYFAALGLVLVAGVGCVVLMGHGGSFLSLVLFLIYLGGMLVVFAYCAALAAEPYPEAWGEWSVL MAYIMLTLLIGMVLGVISVASNPSPYFAALGLVLVAGVGCVVLMGHGGSFLSLVLFLIYLGGMLVVFAYCAALAAEPYPEAWGEWSVL MAYIMLTLLIGMVLGVISVASNPSPYFAALGLVLVAGVGCVVLMGHGGSFLSLVLFLIYLGGMLVVFAYCAALAAEPYPEAWGEWSVL MAYIMLTLLIGMVLGVISVASNPSPYFAALGLVLVAGVGCVVLMGHGGSFLSLVLFLIYLGGMLVVFAYCAALAAEPYPEAWGEWSVL MAYIMLTLLIGMVLGVISVASNPSPYFAALGLVLVAGVGCVVLMGHGGSFLSLVLFLIYLGGMLVVFAYCAALAAEPYPEAWGEWSVL MAYIMLTLLIGMVLGVISVASNPSPYFAALGLVLVAGVGCVVLMGHGGSFLSLVLFLIYLGGMLVVFAYCAALAAEPYPEAWGEWSVL MAYIMLTLLVGMVLGVISVASNPSPYFAALGLVLVAGVGCVVLMGHGGSFLSLVLFLIYLGGMLVVFAYCAALAAEPYPEAWGEWSVL MAYIMLTLLIGMVLGVISVASNPSPYFAALGLVLVAGVGCVVLMGHGGSFLSLVLFLIYLGGMLVVFAYCAALAAEPYPEAWGEWSVL MAYIMLTLLIGMVLGVISVASNPSPYFAALGLVLVAGVGCVVLMGHGGSFLSLVLFLIYLGGMLVVFAYCAALAAEPYPEAWGEWSVL MTYFVLFLGLCFVLGGLAVASNPSPYYGVVGLVLASVAGCAWLLSLGVSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPEAWGDWRVV MMYALFLLSVGLVMGFVGFSSKPSPIYGGLVLIVSGVVGCVIILNFGGGYMGLMVFLIYLGGMMVVFGYTTAMAIEEYPEAWGSGVEV

RGLARGALRAV RGRAWGTMRAV RGRAWGTLRAV WGRAEGSLRVV RGLSRGTLRSV RGRSQGALRAI RGGSYGALRAI RGLARGALRAV RGLARGALRAV RGLARGALRAV RGLARGALRAV RGLARGALRAV RGLARGALRAV RGLARGALRAV RGLARGALRAV RGLARGALRAV RGLARGALRAV RGLARGALRAV RGLARGALRAV RGLARGALRAV RGLARGALRAV RGLTRGAIRAV RGN--------

  Merluccius merluccius (European hake); FR751402 Squalogadus modificatus (Tadpole whiptail); AP008989 Trachyrincus murragi (Roughnose grenadier); AP008990 Bregmaceros nectabanus (Smallscale codlet); AP004411 Physiculus japonicas (Japanese codling); AP004409 Caelorinchus kishinouyei (Mugara grenadier); AP002929 Ventrifossa garmani (Sagami grenadier); AP008991 Lota lota (Burbot); AP004412 Micromesistius poutassou (Blue whiting); FR751401 Pollachius virens (Saithe); FR751399 Pollachius pollachius (Pollack); FR751400 Merlangius merlangius (Whiting); DQ020496 Melanogrammus aeglefinus (Haddock); AM489717 Theragra finnmarchica (Norwegian Pollock); AM489718 Theragra chalcogramma (Alaska Pollock); AB094061 Gadus ogac (Greenland cod); DQ356941 Gadus morhua (Atlantic cod); AM489716 Gadus macrocephalus (Pacific cod); DQ356937 Microgadus proximus (Pacific tomcod); DQ356944 Boreogadus saida (Polar cod); AM919428 Arctogadus glacialis (Arctic cod); AM919429 (bird) Uria lomvia (thick-billed guillemot); X73914 (human) Homo sapiens; KC417443