Nanotechnology Business Incubation: Case Studies in Indonesia DR. ETIK MARDLIYATI, M.ENG Center for Pharmaceutical and Medical Technology Agency for the Assessment and Application of Technology Owner of Nanotech Indonesia, Ltd
DR. NURUL T ROCHMAN, M.ENG, PhD Research Center for Mettalurgy Indonesian Institute of Science (LIPI) Chairman of Indonesian Society for Nano Owner of Nanotech Indonesia, Ltd
INDONESIA SCIENCE & TECHNOLOGY PARK PUSPIPTEK, SERPONG
• Agency for the Assessment and Application of Technology (BPPT) • Indonesia Institute of Science and Technology (LIPI) • Agency for Indonesia Nuclear Energy (BATAN)
Nanotechnology-based Products Nowadays, many nanotechnology-based consumer products are already on the market ... in Indonesia !!!
Survey on more than 150 industries
Source of technology 11% local
%
35%
38%
89% import
Technological level
Simple Nano particle
Intermediate process I
Nano interm. particle
Complex Intermediate process …
Nano product
Estimation for consumtion of nanoparticles from 2005 to 2010 $1~1000/kg
$10~10.000/kg $10~10.000/kg $10~10.000/kg $100~100.000/kg
Luther, Wolfgang, International Strategy and Foresight Report on Nanoscience and Nanotechnology (2004).
SCIENTIFIC ACHIEVEMENTS our team • • • • •
Patents, Designs, Copy Rights : 15 Publications : > 150 Books : > 7 Competitive Grants : > 20 Awards : > 20
THEN WHAT ?? Bringing the invention to marketplace
-1 00 ºC
Pendinginan dengan N2 cair dan ethanol ((-177K)
Termocouple
Jar N2 cair
Milling ball 8
14
ðanol
11 21
15
17
7 3
11
1
2
21 7 12
5
22
21 18
13 20
4 19
9
9
21
6
COMMERCIAL PRODUCTS
16
10
Technology Transfer from Lab to Industry -Learn from Japan (i) Knowing well technology problems in SMEs
Visiting SMEs to gather information
Identifying and solving technical problems
Tech developed in institution (technology supply side)
Making database for priority R&D
Tech need in SMEs (technology demand side)
Survey on more than 150 industries
Problems occurred during the implementation of nanotechnology in national industry Source: Ministry of Industry
5% 11% 11% Human Resources
Financial
41%
Etc.
Information
Inform
32%
Tekno Technology
SDM
Lain-l Dana
Technology Transfer from Lab to Industry -Learn from Japan (ii) Socialization to publics and industries
Public awareness (Association, seminar, homepage, bulletin, media)
Training course and consultation
Research collaboration
“Your Partner in solution & Innovation”
Company Overview Nanotech Indonesia is established with the purpose as a partner for the industries in supporting their growth and delivering technical solutions. With the support from experts and advanced facilities in PUSPIPTEK Serpong, we are committed to deliver high quality service to ensure customer needs can be fulfilled. Started with the focus on laboratory testing, we are now moving forward with various services in technology and technical expertise especially in energy, chemicals, and construction sector.
1st Technology Incubation in PUSPIPTEK, SERPONG
Technology Solution and Innovation
Our Products 1st Indonesian Nano Machine
Technology Solution and Innovation
Case Study 1: Machine for Nanoparticle Production
Our Achievements High energy milling with Sub Zero atmosphere (up to – 100°C)
Pendinginan dengan N2 cair dan ethanol (-177K)
Termocouple
-1 00 ºC Jar N2 cair
Milling ball
Nurul et al. develop planetary ball mill PBM 4A with changeable angle and jar with changeable temperature at subzero (-100ºC). (paten no. S00200700086)
ðanol
High energy ball mill with elliptical three dimension (HEM 3ED) has been commercialized in Indonesia and exported to Malaysia
High Temperature- Rotary Milling that can be operated up to 800°C
7
Case Study 2: Nanoparticles for Cosmetics 3
11
1
2
21 7
Zn O nanoparticle
12
5
22
21 18
13
No irritation Naturally Easy to use
20 4 19
200 nm
9
9 6
21
16
10
Number of experiments
Variation of particle size of ZnO obtained by electric arc 18 16 14 12 10 8 6 4 2 0
17
16 14 11
6
7 5 3 1
50 00 50 00 50 00 50 00 00 1 2 2 3 3 4 4 5 1 1 1 1 1 1 1 1 1 50 10 15 20 25 30 35 40 45
Particle size, nm
USER • Cosmetic industry – Gizi Indonesia, Ltd
• Supplier – PT Tirta Buana Kemindo
ZnO NANOPARTICLES FOR COSMETICS
NANO RICE
• Special order from Gizi Indonesia, Ltd • As active ingredient, UV protection, and opacity agent
Cooming Soon Product
Ingredients : Nano mangosteen, nano rice dan nano zinc oxide
NANO VITAMIN A
Vitamin A encapsulated in chitosan nanoparticles Cream formulation
v.s.
Vit A-nanoencapsulated
Vit A-free
Form
: Suspension (12,3% in water)
Colour
: White
Mean diameter
: <150 nm
pH
: 4,58
Vitamin A content
: 2,29 mg/ml suspension
Stability
: 4x better than vitamin A-free
CLINICAL TESTING Safety Testing Did not cause any allergic reaction in all subjects. Could cause irritation reaction only in 3.9% of all subjects Efficacy Testing - Increased skin moisture content and skin firmness significantly after 4 weeks of application - Gave no positive effect on skin elasticity - Significantly improved skin wrinkle condition after 2 weeks and 4 weeks of application
Mardliyati, et al; Patent Registation No P00201200297; April 18, 2012
Syaffa Cosmetics
Buyer: PT Agro Chomsa, PT Cheria Travel, Personal Offer: PT Qolbi Herba, PT Agro Chomsa, PT Selaras Agro Lestari
Case Study 3: Nano Herbal Commercialization
Development and production of nanoherbal materials Nano-propolis, nano-spirulina, nano-ginseng, nano-curcumin, nanotongkat ali, etc.
Coffee Product with Herbal Nanoparticle (Eurycoma longifolia: Tongkat Ali) for increasing stamina
Coffee Product with Herbal Nanoparticle ginger and gojiberry for increasing stamina
Case Study 4: Pigments for Paint & Coating Material
Ferric Oxide (Fe2O3)
Function • •
•
Physical Description • • • • • • •
Physical state Molecular Weight Boiling Point Melting Point Solubility Stability Corrosivity
•
Polymerization
: Solid : 159.7 g/mole : Decomposes. : 1565°C (2849°F) : Insoluble in cold water. : The product is stable. : Non-corrosive in presence of glass. : No.
• •
feedstock of the steel and iron industries final polish on metallic jewelry and lenses, and historically as a cosmetic. a pigment, under names "Pigment Brown 6", "Pigment Brown 7", and "Pigment Red 101". use in cosmetics. Nanoparticles of iron(III) oxide are biocompatible, wide use in biomedical applications.
Applications • • • • •
Paint Industries Biomedical Polishing jewelry Cosmetics Iron and Steel
34
IRON STONE
IRON SAND
PRODUCTS Black pigment for high temperature paint application Field test : better than commercial one
Red pigment for anti-corrosive application Field test : better than commercial one FIRST TRIAL IN 6500 DWT SHIP
2nd Technology Incubation in Cibinong Science City, Bogor Machine for upscale production
MoU with PT Sigma Utama
CARBON BLACK PIGMENT FROM NATURAL GRAPHITE FOR WHITE BOARD REFILL INK
OUR SERVICES
Community Development
Lembang, Nov 2012 kerja sama dg RCDC
Padang, Des 2012 Collaboration with MoST dan Bappeda
Cilenggang, Bakti Jaya, Babakan, Muncul Januari, Maret, April, Juli 2013
Sumbawa, Maret-April 2013
Kerja sama dg JMHS,JMHI dan UTS
Contact Us Technology Solution and Innovation
Office : Gedung Twink Center Lt. 3 Jalan Kapt Tendean Jakarta R&D: Kawasan PUSPIPTEK Serpong Gd. 410 Balai Inkubator Teknologi BPPT P/F : (021) 7587 0479 E-mail :
[email protected] www.nanotech.co.id dan www.nanoherbal-technology.com Workshop : Batan Lama A-12 Serpong
CONCLUDING REMARK Technology transfer from lab to industry, how? (Start up company?/ Research Collaboration?)
Raw materials for success technology transfer : -knowledge workers (researchers) -Research results (invention) -Entrepreneurial attitude Continuous close interaction with industries Researchers with entrepreneurial attitude
