The Journal of Clinical Investigation EDITED FOR THE AMERICAN SOCIETY FOR CLINICAL INVESTIGATION
EDITORIAL BOARD JAMES L. GAMBLE, EDIO-IN-CHEF ASSOCAwT EDITORS ALLAN M. BUTLER CnuSmT S. KwRR EUGENE M. LANDIS Childrens Hospital, Boston 15, Mass. FRANCS G. BLAxz, New Haven, Conn. C. PHILLIIP MILLER, Chicago, Ill. HERRMAN L. BLUMGART, Boston, Mass. JOHN P. PUSERS, New Haven, Conn. ROBET F. Loss, New York, N. Y. THOMAS M. Rivus, New York, N. Y. The Editorial Committee of the American Society for Clinical Investigation E. V. ALLEN, Rochester, Minn. Rom=r N. NYE, Boston, Mass. WALTER BAUER, Boston, Mass. LowEu. A. RANTZ, San Francisco, Cal. J. S. L. BROWNE, Montreal, P. Q. Tom D. SPIES, Birmingham, Ala. GEORGE T. HARRELL, Winston-Salem, N. C. WILLIAM P. THOMPSON, New York, N. Y. T. R. HARRISON, Dallas, Texas GEORGE W. THORN, Boston, Mass. GEORGE R. HERRMANN, Galveston, Texas Roy H. TURNER, New Orleans, La. J. H. LAWRENCE, Berkeley, Cal. JOSEPH T. WEARN, Cleveland, Ohio RANDOLPH WEST, New York, N. Y.
THE JOURNAL OF CLINICAL INVESTIGATION is designed for the publication of original investigations dealing with or bearing on the problems of disease in man. Each volume will consist of 6 bimonthly issues appearing throughout the calendar year.
Contributions should be sent to the Editorin-Chief, Dr. James L. Gamble, Children's Hospital, 300 Longwood Avenue, Boston 15, Mass. Authors may purchase reprints at scheduled prices. Further information regarding the preparation of manuscripts may be obtained from members of the Editorial Board of the Journal or of the Editorial Committee of the American Society for Clinical Investigation. The subscription price is $10 per volume of 6 bimonthly issues representing the issues of a
calendar year; foreign countries also $10, payable in U. S. funds. Single copies sold when available at $2 a copy. A special subscription rate of $5 per volume of 6 bimonthly issues is offered to medical students, interns, and residents of approved hospitals. Subscriptions are net postpaid. Remittance should be made by draft, check or postal money order, payable to Treasurer.Journal of Clinical Investigation, 300 Longwood Avenue, Boston 15, Mass. Claims for copies lost in the mails must be received within thirty days (domestic), ninety days (foreign), of the date of issue. Changes of address must be received at least two weeks in advance of issue.
The urgent need for early publication of a large inflow of information pertaining to problems of military medicine has been met by a generous grant of funds by The Commonwealth Fund to the American Society for Clinical Investigation. Entered as seoud-class matter Se 6, 1931, at the Post Office at Lanaster, Pa., under the Act of March 3, 1879 Copyright, 1946, Am ercan Society for Clinical Investigation
